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习惯训练与直接视觉生物反的习惯训练在患有慢性便秘的成年人中:一个随机对照试验

Christine Norton¹, Sybil Bannister², Lesley Booth³

¹Faculty of Nursing, Midwifery and Palliative Care, King's College London, London, UK.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

|September 9, 2023

概括

使用生物反 (HTBF) 的习惯训练和标准习惯训练 (HT) 在慢性便秘方面表现出类似的有效性. 简单的干预措施可能与复杂的干预措施一样有效和更具成本效益.

科学领域:

胃肠病学胃肠病学
临床试验临床试验
卫生经济学卫生经济学

背景情况:

慢性便秘会影响生活质量,并且可能对基本治疗不耐药.
使用专家主导的干预措施,如习惯训练 (HT) 和带有生物反的习惯训练 (HTBF).
基于放射生理研究 (INVEST) 的分层治疗是一种潜在的方法.

研究的目的:

为了比较HTBF与HT在慢性便秘方面的有效性.
评估INVEST指导分层是否与标准HT或HTBF相比改善了结果.
评估这些干预措施的成本效益.

主要方法:

一个平行,三臂,单盲随机对照试验.
纳入标准:成年人 (18-70岁) 便秘>6个月,难以接受基本治疗.
主要结局:6个月后患者对便秘生活质量评分的变化.

主要成果:

在HTBF和HT之间,初级结果改善没有统计学上显著的差异.
在INVEST指导干预和非INVEST指导干预之间,结果没有显著差异.
所有干预措施都显示了二次结果的改善,HTBF或INVEST没有更高的成本效益.

结论:

在6个月后,HTBF和INVEST导向治疗对慢性便秘没有比标准HT更有效.
尽管招募人数不足,但研究结果表明,更简单,更少的侵入性干预措施可能同样有效,更具成本效益.
进一步的研究可能有必要在完全招募的队列中证实这些发现.

关键词:

生物反的回报随机对照试验是随机对照试验.便秘便秘便秘便秘一个功能性的功能性功能.胃肠病学胃肠病学

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