在冠状动脉旁路移植手术之前,抑郁症的功能,认知和脑血管方面:测试血管抑郁假设
Joy J Choi1, Bennett Kukla2, Patrick Walsh1
1University of Rochester Medical Center, Rochester, New York, USA.
International journal of geriatric psychiatry
|September 9, 2023
概括
冠状动脉前绕道移植 (CABG) 手术抑郁症与认知和功能缺陷有关,类似于血管抑郁症. 然而,这项研究没有发现与晚年发病或中脑动脉狭窄症的相关性.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 在接受冠状动脉旁路移植 (CABG) 手术的患者中,抑郁症与增加的发病率和死亡率有关.
- 血管抑郁症与需要CABG的患者具有共同的特征,例如血管病变和年龄较大.
研究的目的:
- 为了调查预定进行CABG手术的患者血管抑郁特征的存在.
主要方法:
- 一个前性观察队列研究的横截面分析.
- 手术前的评估包括抑郁症访谈和结构化汉密尔顿 (DISH),抑郁症尺度,跨骨多普勒测试,神经心理测试和临床痴呆症评分 (CDR).
主要成果:
- 在161名受试者中,18人患有严重或轻微的抑郁症,17人有先前的抑郁病史.
- 在CABG前的抑郁与更大的功能障碍 (CDR盒子总和) 和流利性和路径测试的表现较差相关.
- 在CABG前抑郁和中脑动脉 (MCA) 狭窄之间没有发现任何关联.
结论:
- 前CABG抑郁症表现出类似于血管抑郁症的认知和功能障碍.
- 对白质疾病的进一步研究是有必要的,以探索这种患者群体中的血管抑郁假设.
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