孕妇状况对胎儿心脏功能在第二个三个月的影响
Shifa Yao1,2, Tian Yang1,2, Xiaoxiao Kong1,2
1Ultrasound Department, The International Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.
Diagnostics (Basel, Switzerland)
|September 9, 2023
概括
孕妇高血压和孕期糖尿病在第二个三个月内显著影响胎儿心脏功能. 孕产妇的年龄和BMI也会影响胎儿的心脏发育,强调孕产妇健康的重要性.
科学领域:
- 心血管生理学心血管生理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 发展生物学 发展生物学
背景情况:
- 母亲的健康极大地影响胎儿的心血管发育.
- 早期发现胎儿心脏功能障碍至关重要.
研究的目的:
- 调查孕妇年龄,BMI,妊娠高血压 (GH) 和妊娠糖尿病 (GDM) 对胎儿心脏功能的影响.
主要方法:
- 在怀孕21-26周之间对329名母亲进行了胎儿心声图.
- 统计分析包括单因素和多因素回归来评估因素贡献.
主要成果:
- 孕产妇的高血压和GDM严重损害了胎儿心室的抽缩和放缩功能.
- 较高的母体BMI降低了两个心室的透缩功能和左心室的缩功能.
- 孕产妇的年龄对左心室扩张功能有很小的影响.
结论:
- 孕产妇的病情在怀孕第二季度就显著影响胎儿的心脏功能.
- 早期识别和管理孕产妇风险因素对于优化胎儿心脏健康至关重要.
相关概念视频
Fetal Circulation
1.0K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
1.0K
Pathophysiology of Cardiac Performance
702
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
702
Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Development of the Heart
1.0K
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
1.0K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
1.0K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
1.0K


