胃肠道淋巴瘤的内镜和组织病理学特征:一个多中心研究
Quang Trung Tran1,2, Thinh Nguyen Duy3,4, Bao Song Nguyen-Tran4
1Department of Internal Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.
Diagnostics (Basel, Switzerland)
|September 9, 2023
概括
胃肠非霍奇金淋巴瘤在内镜检查期间经常以表面或类型出现. 然而,病变的发作或突出表明有攻击性的亚型,如扩散型大B细胞淋巴瘤.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 外节非霍奇金淋巴瘤 (NHL) 经常影响胃肠道 (GI).
- 了解原发性胃肠道NHL的内镜表现对于及时诊断至关重要.
研究的目的:
- 为了确定初级胃肠非霍奇金淋巴瘤的内镜特征.
- 为了将内镜检测结果与组织学亚型和疾病攻击性相关联.
主要方法:
- 在三个三级转诊医院调查了140名患有初级肠道淋巴瘤的患者.
- 利用图像增强内镜,内镜超声波和组织病理学来评估病变.
- 分析了患者的人口统计,症状,并发症和内镜检查结果.
主要成果:
- 胃是最常见的部位 (61.4%),扩散性大B细胞淋巴瘤 (DLBCL) 和粘膜相关淋巴组织 (MALT) 淋巴瘤是普遍存在的.
- 表面和类型是大多数GI NHL亚型中最常见的内镜检查结果.
- 与型 (MALT,毛囊型) 相比,型和突出的型与攻击性淋巴瘤 (DLBCL,地幔细胞,T细胞) 有显著的关联.
结论:
- 大多数GI NHL亚型具有相似的内镜特征 (表面,类型).
- 在内镜检查中发现有的病变或突出的病变,应该引起对侵袭性肠道肠道NHL的怀疑.
- 意识到内镜特征与组织学亚型之间的联系,可以改善胃肠道淋巴瘤的诊断.
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