心脏移植后续新型非侵入性成像技术:获得的证据和未来的选择
Valeria Pergola1, Giulia Mattesi1, Elena Cozza1
1Cardiology Unit, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, 35128 Padua, Italy.
先进的成像技术有望减少心脏移植受体的侵入性监测. 这些非侵入性方法通过潜在地取代心磁共振 (CMR) 和内心肌瘤活检 (EMB) 来提供更好的患者护理.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 移植医学 移植医学
背景情况:
- 心脏移植 (HT) 是对末期心力衰竭的重要治疗方法,可以改善存活率和生活质量.
- 对HT接受者的常规监测至关重要,但目前的指导方针缺乏关于心声回声计时和内心肌瘤活检 (EMB) 的非侵入性替代方案的具体细节.
- 侵入性冠状动脉血管学 (ICA) 仍然是监测的黄金标准,通常每年进行一次手术后.
研究的目的:
- 对心脏移植患者的非侵入性和节约对比度的成像技术的最新进展进行审查.
- 确定可能取代或减少像ICA和EMB这样的侵入性手术的需要的成像模式.
- 评估HT监测中各种非侵入性成像技术的优缺点.
主要方法:
- 对先进心声回声学 (应变,组织多普勒成像) 的最新文献的综述.
- 评估心脏磁共振 (CMR) 技术 (T1/T2映射) 用于炎症和组织特征.
- 对冠状动脉疾病和移植血管病变的心脏计算机断层扫描 (CCT) 的评估,以及对心脏全移植血管病变 (CAV) 的核心肌输液成像.
主要成果:
- 先进的心声回声学提供了对心脏功能的更深入的了解.
- 通过CMR,可以对炎症和组织特征进行非侵入性评估.
- CCT和核成像显示出评估冠状动脉疾病,移植血管病变以及诊断/预测CAV的潜力.
结论:
- 非侵入性成像技术在改善心脏移植患者护理方面具有变革性的潜力.
- 先进的成像模式,如心声回声,CMR,CCT和核成像,可能会减少对侵入性手术 (ICA,EMB) 的依赖.
- 需要进一步评估每个模式的好处和局限性,以优化对HT接受者的监测策略.
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