在复发性多发性骨髓瘤中使用BCMA导向疗法的不良反应管理:集中审查

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Updated: Jul 9, 2026

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
10:44

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

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Razwana Khanam1, Beth Faiman2, Saba Batool3

  • 1Department of Hospital Medicine, Baystate Medical Center, Springfield, MA 01199, USA.

Journal of clinical medicine
|September 9, 2023
PubMed
概括

针对BCMA的双特异性抗体,抗体-药物合物和CAR T细胞对复发性耐火性多发性髓瘤 (RRMM) 有效. 本综述详细介绍了管理严重的副作用,如细胞因子释放综合征和神经毒性,以改善患者的治疗结果.

关键词:
这些ADC是ADCs.这就是为什么BCMABCMABCMA.它们是BITE,它们是BITE.双特异性抗体 双特异性抗体在CAR-T细胞疗法中.复发的多发性骨髓瘤

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