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在左心室射出小部分 (rEF) 减少 (<50%) 的患者中进行罗塔布拉的安全性和长期结果 (Rota-REF研究)

Mohamed Ayoub¹, Péter Tajti², Ibrahim Akin³

¹Clinic for General and Interventional Cardiology/Angiology, Heart and Diabetes Center NRW, Ruhr University Bochum, 32545 Bad Oeynhausen, Germany.

Journal of clinical medicine

|September 9, 2023

概括

通过皮肤冠状动脉干预 (RA-PCI) 进行旋转性心脏切除术,在减少射出分数 (rEF) 的患者中,与标准PCI相比,在医院内风险较高,但3年后的结果相似. 对于这个患者群体来说,RA-PCI是可行的,也是安全的.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
心血管研究研究心血管研究

背景情况:

减少左心室缩功能 (rEF) 影响皮肤冠状动脉干预 (PCI) 的结果.
旋转性心脏切除术 (RA) 用于复杂的冠状动脉病变,但其在rEF患者的使用尚未得到充分研究.
在这个人群中,评估RA结合PCI (RA-PCI) 的安全性和有效性至关重要.

研究的目的:

评估RA-PCI对左心室缩功能减弱的患者长期临床结果的影响.
为了比较RA-PCI和标准PCI之间的住院和3年主要不良心血管和大脑事件 (MACCE) 在rEF患者中.

主要方法:

在2015年至2019年期间,对4941名经过PCI (有或没有RA) 的rEF患者进行了回顾性分析.
主要终点:住院的MACCE.
二级终点:三年的MACCE.

主要成果:

与标准PCI相比,RA-PCI的住院MACCE率显著高于RA-PCI (7.6%与3.9%,p = 0.0009).
然而,RA-PCI和标准PCI组之间的3年MACCE率相似 (26.40%对26.6%,p = 0.948).

结论:

RA-PCI对于左心室缩功能减弱的患者来说是一种可行且安全的手术.
在这个患者队列中,RA-PCI显示了与标准PCI相似的长期结果.

关键词:

冠状动脉疾病是一种冠状动脉疾病.通过皮肤进行冠状动脉干预.减少左心室喷射小部分.旋转性切除术是一种切除术.

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