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晚期母亲年龄对怀孕结果的影响:一项回顾性多中心研究
Hila Hochler1, Michal Lipschuetz1,2, Yael Suissa-Cohen1
1Department of Obstetrics and Gynecology, Hadassah Medical Center Mount-Scopus, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9765422, Israel.
Journal of clinical medicine
|September 9, 2023
概括
在多胎妇女中,母亲的晚年与剖腹产和新生儿重症监护室 (NICU) 住院率较高有关. 这些发现强调了对计划生育和产妇护理决策的认识的重要性.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 生殖健康 生殖健康
背景情况:
- 母亲年龄是影响怀孕结果的重要因素.
- 之前的研究表明,与晚年孕产妇年龄相关的风险,但根据年龄增量分层的多夫妇妇女的数据需要进一步检查.
研究的目的:
- 调查在多夫妇妇女中晚年母亲年龄和产周期结果之间的关联.
- 将母亲的年龄分为1年和2年的阶段,以确定特定的风险值.
- 将结果与25-30岁分娩的参考组进行比较.
主要方法:
- 多中心回顾性队列研究,涉及302,484名多夫妇女性.
- 从2003年至2021年间在四所大学附属产科部门的分娩中收集的数据.
- 母亲年龄作为连续变量和两年间分析;主要结局是剖腹产和新生儿重症监护室 (NICU) 的入院.
主要成果:
- 剖腹产率随着母亲年龄的增长而增加,从25-30岁年龄组的6.7%上升到43岁以上的女性的20%以上 (p < 0.01).
- 新生儿重症监护室 (NICU) 的入院率也显著增加,从参考组的2.7%增加到45-46岁妇女的6% (p < 0.01).
- 与25-30岁组相比,在所有较先进的母亲年龄层中观察到两种主要结果的统计学上显著增加.
结论:
- 渐进的晚年母亲年龄与剖腹产和多胎妇女入院NICU的比率增加有关.
- 这些发现强调了需要提高对晚年母亲生育期影响的认识.
- 结果强调了在计划生育和优化孕产妇护理策略中考虑这些风险的重要性.
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