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共同感染对人类gammaherpesvirus感染和相关病理学的影响

Prishanta Chinna^1,2,3, Katrin Bratl^1,2,3, Humaira Lambarey^1,2,3

¹International Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town 7925, South Africa.

International journal of molecular sciences

|September 9, 2023

概括

爱斯坦-巴尔病毒 (EBV) 和卡波西病毒.

科学领域:

在瘤学瘤学.
病毒学病毒学
传染性疾病传染性疾病
公共卫生公共卫生

背景情况:

爱斯坦-巴尔病毒 (EBV) 和卡波西肉瘤相关疹病毒 (KSHV) 是致癌的人类疹病毒.
这些病毒造成严重的疾病负担,特别是在免疫抑制个体中.
撒哈拉以南非洲 (SSA) 患有艾滋病毒/艾滋病,结核病和疟疾等传染病的比例很高.

研究的目的:

审查SSA和EBV/KSHV感染中普遍存在的传染病原体之间的关联.
突出同时感染对SSA的EBV和KSHV病理学的影响.
强调在SSA中准确诊断EBV/KSHV相关疾病的重要性.

主要方法:

对SSA流行传染病原体与EBV/KSHV之间已知关联的文献综述.
概述EBV和KSHV生命周期 (潜伏和溶液阶段).
分析由于与常见的SSA疾病的症状模仿导致的诊断挑战.

主要成果:

急性EBV/KSHV感染可以模仿流行SSA疾病,导致误诊.
与常见的SSA病原体的同时感染可能会影响EBV/KSHV的传染过程.
在SSA中,EBV和KSHV非常普遍,导致大量的发病率和死亡率.

结论:

在SSA中,准确识别EBV/KSHV病理的风险因素和诊断至关重要.
了解共同感染对于管理该地区的EBV和KSHV相关疾病至关重要.
在SSA中,需要提高对瘤性疹病毒的认识和诊断警.

关键词:

在 COVID-19 疫情中,爱斯坦-巴尔病毒 (EBV或HHV-4)卡波西的肉瘤相关的疹病毒 (KSHV或HHV-8)结核菌菌菌 (Mtb) 的存在原菌 (Plasmodium falciparum) 是一种有毒的病毒.撒哈拉以南非洲 (SSA)人类免疫缺陷病毒 (HIV)疟疾疟疾是一种疾病.严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)

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