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Updated: Jul 16, 2025

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
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A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

Published on: October 16, 2015

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基替代物对双甲化合物的影响与人血清白蛋白的相互作用:从光谱技术和计算机模拟中探索

Huan Zhang1, Ruirui Cai2, Chaolan Chen2

  • 1School of Life Sciences, Nanchang University, Nanchang 330031, China.

International journal of molecular sciences
|September 9, 2023
PubMed
概括

化双乙醇A (BPA) 化合物,四博双乙醇A (TBBPA) 和四双乙醇A (TCBPA),与人体血清白蛋白 (HSA) 结合. 由于疏水性相互作用,TBBPA表现出更高的亲和力,影响HSA结构.

关键词:
计算机模拟的计算机模拟.素替代双乙醇A是一种素替代双乙醇.人类血清白蛋白的人类血清白蛋白.频谱学技术的使用.

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Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of GoldIII08:26

Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of GoldIII

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Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride

Radical substitution reactions can be used to remove functional groups from molecules. The hydrogenolysis of alkyl halides is one such reaction, where the weak Sn–H bond in tributyltin hydride reacts with alkyl halides to form alkanes. Here, the reagent Bu3SnH yields tributyltin halide as a byproduct.
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Alkyl Halides

Structural Properties
Alkyl halides are halogen-substituted alkanes wherein one or more hydrogen atoms of an alkane is replaced by a halogen atom such as fluorine, chlorine, bromine, or iodine. The carbon atom in an alkyl halide is bonded to the halogen atom, which is sp3-hybridized and exhibits a tetrahedral shape.
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Benzylic halogenation takes place under conditions that favor radical reactions such as heat, light, or a free radical initiator like peroxide.
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