准肠眼轴:面对眼部疾病的新兴策略
Lucrezia Irene Maria Campagnoli1, Angelica Varesi2, Annalisa Barbieri1
1Department of Drug Sciences, Unit of Pharmacology, University of Pavia, 27100 Pavia, Italy.
International journal of molecular sciences
|September 9, 2023
概括
肠道微生物群 (GM) 通过肠-眼轴影响眼睛健康. 调节转基因可能为眼睛疾病提供新的治疗方法,如玻璃眼和干眼.
科学领域:
- 微生物学 微生物学
- 眼科医生 眼科 眼科
- 胃肠病学 胃肠病学
背景情况:
- 人体拥有多样化的微生物群,包括眼睛表面的微生物群,这对平衡至关重要.
- 最近的研究强调了肠道微生物群 (GM) 与眼睛健康之间的联系,表明肠-眼睛轴.
研究的目的:
- 探索肠道微生物群与眼睛健康之间的联系.
- 在眼科疾病的背景下了解肠眼轴.
主要方法:
- 对调查肠眼轴的研究进行文献综述.
- 分析证据,将肠道微生物群失调与眼部疾病联系起来.
主要成果:
- 肠眼轴与与年龄相关的黄斑变性病变,脑膜炎,糖尿病视网膜病变,眼睛干燥和玻璃眼有关.
- 眼睛表面的微生物群在防止病原体殖民方面发挥着作用.
结论:
- 了解肠道微生物群在眼睛疾病中的作用,可以为新的治疗策略提供信息.
- 通过益生菌,益生菌或便微生物移植调节肠道微生物群可能有助于管理眼部疾病.
相关概念视频
Open Angle Glaucoma: Treatment
477
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
477
Angle Closure Glaucoma: Treatment
559
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
559
Accessory Structures of the Eye
1.6K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.6K
Glaucoma: Overview
618
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
618


