基于酸盐,酸盐和果果果的新型双混合型骨水泥
Piotr Pańtak1, Joanna P Czechowska1, Ewelina Cichoń2
1Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Mickiewicza Av. 30, 30-058 Krakow, Poland.
International journal of molecular sciences
|September 9, 2023
概括
这项研究开发了新的双混合骨替代品,使用α-三酸和酸/酸盐. 在液态阶段的果果果增强了性能,并创建了具有双设置系统的可注射材料.
科学领域:
- 生物材料科学 生物材料科学
- 材料工程 材料工程 材料工程
- 生物医学工程 生物医学工程
背景情况:
- 骨替代品对于骨缺陷的修复至关重要.
- 开发具有可控制定位时间的可注射骨替代品仍然是一个挑战.
- 混合生物材料具有提高生物相容性和机械性能的潜力.
研究的目的:
- 为了研究液相组合对双杂交骨替代品特性的影响.
- 开发具有双设置系统的新型可注射骨替代品.
- 探索果果在修改物理化学特性的作用.
主要方法:
- 使用α-三酸 (α-TCP) 和酸/酸盐 (HA/CTS) 颗粒合成的双杂交生物材料.
- 使用二酸盐溶液和类果果凝作为液态相.
- 通过FTIR,XRD,Gillmore针,SEM和体外化学稳定性测试来表征材料.
主要成果:
- 材料表现出双重设置行为,初始设置时间从4.5到30.5分钟,最终设置时间从7.5到55.5分钟.
- 压力强度在5.75到13.24MPa之间.
- 添加类果实素增强了物理化学特性,并使其可注射.
结论:
- 液态阶段的果果果是开发可注射的双混合骨替代品的关键,具有可调节的双重设置特性.
- 果果的比例可以控制材料的物理化学特性.
- 这些发现为先进的骨再生疗法提供了有希望的途径.
更多相关视频
06:05Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
Published on: July 14, 2023
1.0K
09:35Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
9.8K
相关概念视频
Bone Remodeling
38.4K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.4K
The Bone Matrix
3.2K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
3.2K
