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Updated: Jul 16, 2025

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通过以-CoA 酸酶/酸酶的合理设计来生物合成瓦尼林

Qi Ye1, Weizhuo Xu2, Yanan He1

  • 1School of Life Sciences and Biopharmaceuticals, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.

International journal of molecular sciences
|September 9, 2023
PubMed
概括

研究人员设计了enoyl-CoA hydratase/lyase (Ech) 酶,以改善香草素的生物合成. 三种Ech突变 (F74W,Q147R,ΔN1-11) 显著增加了素产量,为香味化合物生产的酶优化提供了洞察力.

关键词:
生物合成生物合成烯基-CoA酸酶/酸酶的使用情况分子动力学分子动力学合理的设计理性的设计.瓦尼林氨酸是一种

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