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Updated: Jul 16, 2025

Diagonal Method to Measure Synergy Among Any Number of Drugs
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解释药物组合的协同作用机制,使用基于注意力的层次图汇集

Zehao Dong1, Heming Zhang2, Yixin Chen1

  • 1Department of Computer Science & Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.

Cancers
|September 9, 2023
PubMed
概括

这项研究引入了一个可解释的图形神经网络 (GNN),用于预测协同药物组合. 新的SANEpool层提高了预测准确性,并揭示了关键的治疗目标和协同作用机制.

关键词:
药物反应预测 药物反应预测图形神经网络的神经网络可以解释的解释性.

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