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一个患有可切除或边缘切除胰腺癌的患者应该如何治疗-全面审查

Daria Kwaśniewska¹, Marta Fudalej^1,2, Paweł Nurzyński¹

¹Department of Oncology, Central Clinical Hospital of the Ministry of Interior and Administration, 02-507 Warsaw, Poland.

|September 9, 2023

概括

胰腺管道腺癌 (PDAC) 管理正在发展. 本研究概述了可切除和边缘切除PDAC的多学科方法,重点关注新辅助疗法以改善结果.

科学领域:

手术瘤学手术瘤学
胃肠病学胃肠病学
医学瘤学医学瘤学

背景情况:

胰腺管腺癌 (PDAC) 的长期存活率很低,手术切除是唯一可能治愈的选择.
准确的患者选择和多学科决策对于优化PDAC手术结果至关重要.
早期复发在PDAC中很常见,通常是由于先前存在的微转移.

研究的目的:

为可切除PDAC (R-PDAC) 和边界切除PDAC (BR-PDAC) 提出一个多学科的管理概念.
强调新辅助疗法 (NAT) 在改善切除率和患者存活率方面的作用.
为PDAC提供关于最佳顺序多式联通NAT策略的指导.

主要方法:

对管理R-PDAC和BR-PDAC的当前知识和机构经验的审查.
讨论2017年建立的R-PDAC和BR-PDAC的标准化定义.
整合放射和外科手术技术,以评估切除能力.

主要成果:

新辅助疗法 (NAT) 对于改善PDAC中负边缘切除率至关重要.
NAT的目标是实现局部控制和根除微转移,从而延长存活时间.
标准化定义有助于识别可能受益于NAT的患者.

结论:

多学科的方法对于R-PDAC和BR-PDAC的有效治疗管理至关重要.
优化顺序多式联网是PDAC未来研究的一个关键领域.
改善患者选择和新辅助策略可以提高胰腺癌的存活率.

关键词:

一个辅助的辅助者.边界切除可切除的化学疗法化疗化疗这是一种新辅助剂.胰腺癌是一种癌症.辐射疗法辐射疗法可切除的可切除物切除切除切除切除

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