治疗勃起功能障碍的食补充剂:对市场上销售的产品的分析,系统审查,元分析和合理使用
Gabriel Cosmin Petre1, Francesco Francini-Pesenti2, Amerigo Vitagliano3
1Unit of Andrology and Reproductive Medicine & Centre for Male Gamete Cryopreservation, Department of Medicine, University of Padova, 35100 Padova, Italy.
许多治疗勃起功能障碍 (ED) 的食补充剂缺乏经过证明的疗效. 一项审查发现,大多数男性性表现产品含有微不足道的活性成分剂量或缺乏证据,很少有人显示潜在的益处.
科学领域:
- 男人性健康 男人性健康
- 营养药品和补充剂 营养药和补充剂
- 勃起功能障碍研究 研究勃起功能障碍研究
背景情况:
- 对于男性性表现,特别是勃起功能障碍 (ED) 的营养药品越来越受欢迎.
- 食补充剂 (DSs) 在网上广泛销售,但它们的有效性往往没有得到证实.
- 越来越多的消费者兴趣和制造商收入凸显了评估这些产品的必要性.
研究的目的:
- 评估饮食补充剂配方对男性性能的潜在疗效.
- 确定有效成分 (EIs) 和它们的最小有效每日剂量 (mEDs) 来改善勃起功能.
- 用分数方法分析在意大利销售的DS产品.
主要方法:
- 系统的文献审查,以评估DS的影响,并确定EI和mEDs.
- 对特定营养保健品的疗效进行元分析.
- 对在意大利销售的DS产品应用的评分系统.
主要成果:
- 一些营养药物如帕纳克斯人参,Tribulus terrestris和L-氨酸显示出改善男性性功能的潜力.
- 分析后的补充剂中,只有8%处于高效集群中,12%处于低效集群中.
- 显著的大多数 (80%) DS 符合没有预期疗效的标准.
结论:
- 在意大利销售的大多数用于男性性表现的DS含有可忽略的剂量或没有证据的多种物质.
- 许多DS中的成分和剂量的组合使人们对现实世界的有效性产生了怀疑.
- 需要对ED专注的食补充剂进行进一步的研究和监管审查.
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