老年营养风险指数是预测所有年龄段成人死亡率的最佳评估参数 血液透析患者:一项韩国基于人口的研究
Do Hyoung Kim1, Young-Ki Lee1, Hayne Cho Park1
1Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul 07441, Republic of Korea.
Nutrients
|September 9, 2023
概括
老年营养风险指数 (GNRI) 截止值为90.8,有效预测血液透析患者的死亡率. 低于90.8的GNRI表明HD患者的死亡风险明显更高.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 老年营养风险指数 (GNRI) 是评估营养状况的工具.
- 预测血液透析 (HD) 患者的死亡风险对于临床管理至关重要.
- 建立最佳查门对于有效的患者护理至关重要.
研究的目的:
- 确定GNRI的最佳切割值,用于预测在接受维护血液透析的韩国患者中全因死亡率.
- 验证GNRI在这个特定患者群体中作为预后指标的实用性.
主要方法:
- 利用了2015年韩国血液透析质量评估数据.
- 采用多变量考克斯回归模型和哈雷尔的C指数来确定最佳的GNRI切线.
- 分析了34933名维持血液透析患者的数据,平均随访时间为53.7个月.
主要成果:
- 确定预测死亡率的最佳GNRI截止值为90.8.
- 具有GNRI<90.8的患者的粗死亡率为160.4/1000人年,而具有GNRI≥90.8.8的患者的粗死亡率为73.2/1000人年.
- 在完全调整的考克斯模型中,GNRI<90.8与死亡风险增加1.78倍有关.
结论:
- 建议GNRI最佳切割值为90.8,用于预测维护血液透析患者的死亡率.
- 该GNRI作为一个有价值和验证的工具,用于在这一群体的风险分层.
- 较低的GNRI得分 (<90.8) 与血液透析患者的死亡风险增加有显著联系.
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