改性大米Arabinoxylan由Lentinus edodes菌酶作为健康和衰老的免疫药物-一个全面的文献审查
Soo Liang Ooi1, Peter S Micalos2, Sok Cheon Pak1
1School of Dentistry and Medical Sciences, Charles Sturt University, Bathurst, NSW 2795, Australia.
Molecules (Basel, Switzerland)
|September 9, 2023
概括
子阿拉比诺基兰化合物 (RBAC) 增强了健康和老年人的免疫功能. 这种免疫调节营养药可支持先天性和适应性免疫力,为病毒感染提供潜在的预防性益处.
科学领域:
- 免疫学 免疫学 免疫学
- 营养学科学 营养学科学
- 胃肠病学 胃肠病学
背景情况:
- 米阿拉比诺西兰化合物 (RBAC) 是从米中提取的复杂异多聚糖.
- 它是用Lentinus edodes*菌进行酶处理,形成一个强大的免疫调节剂.
研究的目的:
- 审查RBAC作为免疫调节营养药的生物活动和机制.
- 评估它在一般健康和老年人中的有效性.
主要方法:
- 一个综合性审查37个主要研究文章,重点关注RBAC (主要是Biobran MGN-3).
- 对研究RBAC与消化道和免疫细胞相互作用的研究分析.
主要成果:
- RBAC通过促进巨细胞化和自然杀手细胞活性来增强先天免疫力.
- 它通过树突细胞成熟来增强适应性免疫力,促进T和B淋巴细胞的增殖.
- RBAC调节过敏反应,炎症和血管生成,证明了免疫健康的安全性和有效性,特别是在老年人群中.
结论:
- RBAC是一种安全有效的营养药,用于改善免疫健康,特别是在免疫功能减弱的老年人中.
- 临床试验表明,预防性治疗对病毒感染有好处,并且改善了老年参与者的生活质量.
- 进一步研究RBAC的生物可用性,药理动力学和药理动力学是合理的,与更大的人类研究一起.
更多相关视频
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
3.9K
11:44Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
Published on: January 19, 2022
2.5K
相关概念视频
The Effect of Aging on Tissues
2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
Liver Regeneration
3.3K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
3.3K
Stem Cell Therapy for Tissue Regeneration
4.1K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.1K
Mesenchymal Stem Cells
4.8K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
4.8K
