关于通过离子液体辅助水性双相系统提取和净化Acanthopanax senticosus多的研究
Ying Li1, Xiaoli Li1, Xueyan Wang1
1Shandong Provincial Institute of Chinese Veterinary Medicine, Liaocheng University, Liaocheng 252000, China.
Molecules (Basel, Switzerland)
|September 9, 2023
概括
一种使用离子液体 (ILs) 在水性双相系统 (ATPS) 中的新型绿色方法有效地从Acanthopanax senticosus中提取多. 这种离子液体辅助ATPS (IL-ATPS) 为传统提取技术提供了简单,快速和有效的替代方案.
科学领域:
- 绿色化学 绿色化学
- 自然产品提取 提取自然产品
- 分离科学 分离科学
背景情况:
- 多是一种有价值的化合物,具有各种健康益处.
- 传统的多提取方法可能是低效和不环保的.
- 阿坎托帕纳克斯 (Acanthopanax senticosus) 是一种富含生物活性化合物的植物,包括多.
研究的目的:
- 开发和优化从Acanthopanax senticosus中提取多的绿色提取方法.
- 调查使用离子液体 (ILs) 作为辅助剂在水性双相系统 (ATPS) 中用于聚提取.
- 使用宏树脂净化提取的多,并研究运动机制.
主要方法:
- 使用[OMIM]Br,乙醇和NaH2PO4.4建立了离子液体辅助的水性双相系统 (IL-ATPS).
- 提取参数的优化,包括乙醇和NaH2PO4度,IL百分比,固体-液体比,温度,pH和时间.
- 使用AB-8宏树脂和活性炭净化聚醇,分析吸附动力学和脱色.
- 对离子液的可重复使用性进行评估.
主要成果:
- 最佳的IL-ATPS涉及[OMIM]Br辅助乙醇/NaH2PO4,在特定条件下达到15.90毫克/g的多提取率 (32%的乙醇,25%的NaH2PO4,9%的IL,1:40的比率,50°C,pH4.0,50分钟).
- 优化的宏树脂净化参数包括3.5 BV·h-1的流量,40 mL的样品体积,80 mL的化剂体积 (85%的乙醇).
- 4%的活性炭度提供了最佳的脱色 (76.81%),离子液回收达到81.12%.
结论:
- 开发的IL-ATPS是一种高效和绿色的方法,用于从Acanthopanax senticosus中提取多.
- 这种方法比传统技术具有显著的优势,包括简单,节省时间和高效率.
- 该研究表明IL-ATPS在可持续提取有价值的多化合物的潜力.
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