在巴西圣保罗新热带灵长类动物中检测出疹病毒
Isabella Naomi Furusato1, Ketlyn Bolsachini Figueiredo1, Ana Carolina Souza Ramos de Carvalho1
1Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.
概括
在巴西超过25%的新热带灵长类 (NTPs) 中检测到疹病毒,在成人和被囚禁的动物中患病率更高. 这突显了动物传播疾病的风险,以及对灵长类动物种群的持续监测的需要.
科学领域:
- 兽医病毒学 兽医病毒学
- 灵长类健康 灵长类健康
- 保护生物学 保护生物学
背景情况:
- 人与非人类灵长类动物 (NHPs) 之间的疹病毒传播对人类健康和危灵长类动物物种都有重大风险.
- 新热带灵长类 (NTPs) 越来越受到息地丧失和人类侵占的威胁,使它们易受新型病原体的侵害.
研究的目的:
- 在巴西圣保罗的一个多样化的NTP队伍中识别疹病毒基因组.
- 评估这些灵长类动物群体中特定疹病毒的流行率.
- 调查影响NTP中疹病毒检测率的因素.
主要方法:
- 总共有242个NTP (Callithrix sp.,Alouatta sp.,Sapajus sp.和Callicebus sp.) 进行了测试. 进行了采样.
- 泛疹病毒聚合酶链反应 (PCR) 和测序用于病毒检测.
- 使用统计分析来评估动物年龄和养条件对检测率的影响.
主要成果:
- 在25.6%的采样NTP中检测到疹病毒基因组.
- 确定的特定病毒包括Callitrichine gammaherpesvirus 3 (16.1%),人类alphaherpesvirus 1 (6.1%),Alouatta macconnelli cytomegalovirus (2.1%),以及Cebus albifrons lymphocryptovirus 1 (0.83%). 这三种病毒都存在于人类中.
- 在成年NTP和在人类护理下居住的人群中,疹病毒的检测显著更高.
结论:
- 这项研究证实了巴西NTP中各种疹病毒的传播,包括具有潜在动物传染影响的菌株.
- 成人和被囚禁的灵长类动物代表了疹病毒的关键储库,这强调了监测这些群体的重要性.
- 定期监测NTP种群对于预防动物病发作和减轻物种间疾病传播至关重要.
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