在研究管道中嵌入实施科学
Leah L Zullig1,2, Connor Drake1,2, Devon K Check2
1Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Translational behavioral medicine
|September 9, 2023
概括
实施科学可以在医疗保健研究中弥合"死亡之谷",加速将基于证据的干预措施转化为实践. 嵌入这些原则可以确保科学发现更有效地改善患者的健康.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 实施科学 实施科学
背景情况:
- 目前的研究范式对于将发现转化为现实世界的临床实践是缓慢和低效的.
- 在证据生成和实际实施之间存在很大的差距,被称为"死亡之谷".
- 只有14%的基于证据的干预措施得到实施,通常是17年后.
研究的目的:
- 建议在整个研究管道中嵌入实施科学原则.
- 为了应对将科学发现转化为现实世界的挑战.
- 概述对能力建设和研究设计的影响.
主要方法:
- 审查当前的证据生成和翻译范式.
- 提出一个新的研究范式,整合实施科学.
- 确定在实施科学中的能力建设所必需的组件.
主要成果:
- 嵌入实现科学可以有效地将发现转化为现实世界的背景.
- 能力建设,研究团队组成和研究设计是关键影响.
- 一个新的研究范式强调科学家对翻译的责任.
结论:
- 实施科学提供了一个框架,可以弥合研究和实践之间的差距.
- 整合实施科学对于最大限度地提高健康研究的影响至关重要.
- 需要采取积极的方法来确保科学进步有利于患者的健康.
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