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Updated: Jul 16, 2025

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以结构为导向的方法来修改人体脱糖酶-1 (hDJ-1) 蛋白质的基质特异性

Sera A Fernandes1, Subrata Dasgupta2, Rashmi S Tupe1

  • 1Symbiosis School of Biological Sciences, Symbiosis International (Deemed University), Lavale, Pune, 412115, Maharashtra, India.

Biochemical and biophysical research communications
|September 9, 2023
PubMed
概括

通过修改一个关键的谷氨酸酸盐残留物来研究人类降糖酶-1 (hDJ-1) 酶活性. 这种单一的氨基酸变化增强了hDJ-1的功效.

关键词:
酶动力学 酶动力学葡萄糖化是指糖化的一种方式.人类降糖酶-1的人类降糖酶-1分子对接是分子对接.局部导向的突变发生.基质特异性 基质特异性

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