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Updated: Jul 16, 2025

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一个反应性物种反应模块,用于整合到基因组规模的代谢模型中,以获得更好的洞察力:应用于癌症

Subasree Sridhar1, Prerna Bhalla2, Justin Kullu2

  • 1Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences Building - 1 and 2, Indian Institute of Technology Madras, Chennai, 600 036, India; Centre for Integrative Biology and Systems medicinE, Indian Institute of Technology Madras, Chennai, 600 036, India.

Metabolic engineering
|September 9, 2023
PubMed
概括

这项研究引入了一个新的模块,用于在癌症研究的基因组规模代谢模型中建模反应性物种 (RS). 整合RS反应改善了癌症代谢模型,揭示了途径失调并指导了化的向策略.

关键词:
癌症代谢 癌症代谢铁化是铁化的一种.基因组规模的代谢模型有反应性的物种.

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