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相关概念视频

Observational Studies01:11

Observational Studies

8.7K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
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Longitudinal Research02:20

Longitudinal Research

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Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
147

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[Translated article] Efficacy of early versus delayed spinal cord decompression in neurological recovery after traumatic spinal cord injury: Systematic review and meta-analysis.

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[Translated article] SCIWORA in children. A rare clinical entity: Ambispective study.

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相关实验视频

Updated: Jul 16, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

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在儿童中SCIWORA. 一个罕见的临床实体:双重研究.

L M Romero-Muñoz1, M Peral-Alarma1, A Barriga-Martín1

  • 1Servicio de Cirugía Ortopédica y Traumatología, Hospital Nacional de Parapléjicos, Toledo, España.

Revista espanola de cirugia ortopedica y traumatologia
|September 9, 2023
PubMed
概括

没有放射性异常的脊髓 (SCIWORA) 不成比例地影响儿童,由于机动车辆事故,大多数伤害发生在椎. 通过AIS等级D评估的功能恢复,在31%的患者中观察到退院一年后,并在五年内保持稳定.

科学领域:

  • 神经学 神经学
  • 整形外科 整形外科 整形外科
  • 创伤外科 手术 创伤外科

背景情况:

  • 没有放射性异常的脊髓损伤 (SCIWORA) 由于其发病率低但功能影响显著,因此具有诊断挑战.
  • 了解SCIWORA的流行病学和长期结果对于有效的患者管理至关重要.

研究的目的:

  • 为了调查SCIWORA的流行病学特征.
  • 评估SCIWORA患者的功能结果,长期随访长达10年.

主要方法:

  • 进行了一项观察性,纵向的两样性队列研究.
  • 收集的数据包括人口统计,损伤机制,MRI发现,神经状态 (ASIA损伤量表 - AIS) 和功能评分 (SCIM III,NDI,Oswestry,SV-QLI/SCI).
  • 分析了13名SCIWORA患者,并将在2022年10月重新评估.

主要成果:

  • SCIWORA患者的平均年龄为4岁,77%是男性. 大多数受伤 (54%) 发生在椎,主要是机动车辆事故 (77%) 造成的.
  • 在入院时,31%的患者有AIS等级A,31%的患者有AIS等级C. 功能性得分显示从入院到退院的情况有所改善 (SCIM III:28.5/42).
  • 长期随访显示,31%的患者在1年内达到AIS等级D,这一比例在5年内保持不变. 在伤害机制/MRI发现和年龄/MRI发现之间没有发现显著的相关性.
关键词:
儿童医院的年龄.造成骨髓损伤.脊髓是脊髓的一部分.儿科 儿科 儿科斯基沃拉 (SCIWORA) 是一个在脊髓中,脊髓是最重要的.脊髓损伤导致的脊髓损伤创伤是一个创伤.这是一种创伤主义 (traumatismo).

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结论:

  • SCIWORA主要影响幼儿,其中高比例的椎脊椎损伤与机动车辆事故有关.
  • 很大一部分患者在一年内达到一定程度的功能恢复 (AIS等级D),并保持长期.
  • 该研究强调了早期识别和管理SCIWORA的重要性,以优化这个脆弱人群的功能结果.