模拟中的诺病毒动态强调了与当前测试和净化协议相关的潜在食品安全问题
Paul McMenemy1, Adam Kleczkowski1, Nick G H Taylor2
1University of Strathclyde, 16 Richmond Street, Glasgow, G1 1XQ, United Kingdom; University of Stirling, Airthrey Road, Stirling, FK9 4LA, United Kingdom.
Food microbiology
|September 9, 2023
概括
与生相关的诺罗病毒疫情凸显了当前测试的局限性. 新的研究表明,含有隐藏的诺罗病毒,需要更长的净化时间和总病毒载量评估,以更安全地消费贝类.
科学领域:
- 食品安全 食品安全
- 海洋微生物学 海洋微生物学
- 胃肠病学 胃肠病学
背景情况:
- 诺罗病毒是全球病毒性胃肠炎的主要原因,经常与生的消费有关.
- 目前的贝类安全评估使用大肠杆菌作为诺罗病毒的代理,这是不充分的.
- 现有的诺罗病毒检测只检测的消化道中的病毒,可能低估了总病毒载量.
研究的目的:
- 模拟内的诺病毒封存,考虑可观测和神秘的部分.
- 为了确定在中进行准确的诺罗病毒检测的最佳净化时间.
- 为了为贝类安全提供未来的诺罗病毒立法信息.
主要方法:
- 开发了一个数学模型,将诺罗病毒绑定纳入内可观察和神秘的隔间.
- 分析了净化试验数据以验证模型预测.
- 将模型输出与现有关于贝类病毒衰变的研究进行了比较.
主要成果:
- 贝类中的总诺罗病毒水平在早期净化过程中达到峰值,受到神秘诺罗病毒的比例的影响.
- 病毒水平表现出多相衰变模式,与净化试验数据和其他研究一致.
- 确定62小时为诺罗病毒检测前推的净化时间.
结论:
- 未来的诺病毒立法必须考虑的总病毒载量,而不仅仅是收获水质.
- 目前的测试方法可能不能完全反映与食相关的诺罗病毒风险.
- 实施62小时的净化期可确保检测或清除神秘的诺罗病毒,提高贝类安全标准.
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