埃奇诺科克细粒细胞囊液通过诱导巨细胞中的基因组脱甲基酶KDM5B来抑制炎症反应

Xiaopeng Wang1,2, Ruolin Lin1,2, Chunxue Fu1,2

  • 1NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang, China.

Parasites & vectors
|September 9, 2023
PubMed
概括

Echinococcus granulosus囊液通过促进KDM5B表达和减少H3K4me3修饰在炎症基因促进器中抑制巨细胞炎症. 这种表观遗传机制有助于寄生虫逃避宿主免疫反应.