相关实验视频

Updated: Jul 16, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

Published on: October 14, 2022

使用HiFi和Hi-C数据的第一个高质量的染色体水平基因组Eretmochelys imbricata使用HiFi和Hi-C数据

Yusong Guo¹, Jiao Tang¹, Zixuan Zhuo¹

¹Key Laboratory of Aquaculture in South China Sea for Aquatic Economic Animal of Guangdong Higher Education Institutes, Fisheries College, Guangdong Ocean University, Zhanjiang, 524088, China.

Scientific data

|September 9, 2023

概括

极度危的海 (Eretmochelys imbricata) 现在拥有了高质量的基因组序列. 这一突破有助于理解其演变,并为这种重要的海洋物种制定保护战略.

科学领域:

海洋生物学海洋生物学
基因组学就是基因组学.
保护遗传学保护遗传学

背景情况:

鷹嘴海 (Eretmochelys imbricata) 在全球面臨嚴重危.
它的基因组序列以前没有被描述,这阻碍了保护工作.

研究的目的:

为了组装一个高质量的,染色体水平的基因组序列为Eretmochelys imbricata.
分析它的进化关系和遗传特征.

主要方法:

利用高保真度 (HiFi) 读取和Hi-C技术进行基因组组装.
进行了基因预测和进化分析.

主要成果:

组装了一个2,138.26 Mb的基因组,将97.52%的基因定在28个染色体上.
预测了20206个编码蛋白质的基因.
揭示了3800万年前与Chelonia mydas的分歧,具有丰富的嗅觉和与衰老相关的基因.

结论:

在染色体水平的基因组的Eretmochelys imbricata提供了一个宝贵的资源.
促进对海进化,适应和保护策略的进一步研究.

更多相关视频

Generation of Genome-wide Chromatin Conformation Capture Libraries from Tightly Staged Early Drosophila Embryos

Generation of Genome-wide Chromatin Conformation Capture Libraries from Tightly Staged Early Drosophila Embryos

Published on: October 3, 2018

Capturing Chromosome Conformation Across Length Scales

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

相关概念视频

Genomic DNA in Eukaryotes

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.