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NSO-异环PAHs-受控暴露研究显示,高急性水生毒性

Göksu Çelik¹, Stefan Stolte¹, Marta Markiewicz¹

¹Institute of Water Chemistry, Technische Universität Dresden, Bergstr. 66, D-01062 Dresden, Germany.

Journal of hazardous materials

|September 10, 2023

概括

异环多环芳 (异环PAH) 对水生生态系统构成威胁. 被动剂量显示对藻类和水的高毒性,表明存在重大环境风险.

科学领域:

环境科学环境科学
生态毒理学生态毒理学
水生毒理学水生毒理学

背景情况:

异环多环芳 (异环PAH) 是一种环境污染物.
它们的存在威胁到水生生态系统的健康.
了解它们的毒性对于风险评估至关重要.

研究的目的:

调查异环PAH对水生生物的急性毒性.
为了确定膜水分区系数 (KMW) 和毒性之间的关系.
为了比较使用标准协议的毒性测试与被动剂量测试.

主要方法:

在海洋细菌 (Aliivibrio fischeri),绿藻 (Raphidocelis subcapitata) 和水 (Daphnia magna) 上对异环PAH的急性毒性测试.
使用被动剂量来保持稳定的暴露度.
测量了每个化合物的膜-水分区系数 (KMW).

主要成果:

异环PAH对A. fischeri的毒性较低,但对R. subcapitata和D. magna的毒性较高.
毒性随着KMW值的增加而增加,这表明非极性麻醉是主要的作用模式.
与标准方法相比,被动剂量显示出更高的毒性,这是由于后者中化合物损失很大.

结论:

异环PAH对水生生物,特别是藻类和无脊椎动物构成重大风险.
非极性麻醉是可能的毒性机制.
被动剂量是对疏水化合物的精确水生毒性测试的优越方法.

关键词:

对水生有毒性的水生毒性异环化合物异环化合物作用方式作用方式它们是NSO-PAHs.消极的剂量被动的剂量.

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