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Updated: Jul 16, 2025

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
09:19

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Published on: February 6, 2015

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鉴定了针对癌细胞中的p97/NPL4通路的新型滴氧碳酸盐-铜复合体

Martin Loffelmann1, Zdeněk Škrott1, Dušana Majera1

  • 1Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 1333/5, Olomouc, 779 00, Czech Republic.

European journal of medicinal chemistry
|September 10, 2023
PubMed
概括

滴甲酸盐 (DTC) 的铜复合体可以有效地向和聚合NPL4蛋白,诱导蛋白质毒性应激和癌细胞死亡. 这一发现突出了DTCs-铜复合体作为癌症药物开发的有希望的候选人.

关键词:
癌症 癌症 癌症 癌症复杂的铜复合体 铜复合体这就是CuETET的意义.二甲基碳酸盐的二甲基碳酸盐.在 NPL4 蛋白质中,蛋白质毒性压力是一种蛋白质毒性压力.

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