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Hu Hei¹, Ziyu Luo¹, Chen Zheng¹

¹Department of Thyroid and Neck, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450008, China.

|September 10, 2023

概括

淋巴结比率 (LNR) 在乳头甲状腺癌 (PTC) 中影响术后的甲状腺蛋白 (Tg) 水平. 较高的LNR与手术后不完全的生化反应有关,表明其预后意义.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
手术病理学手术病理学

背景情况:

乳头甲状腺癌 (PTC) 是最常见的内分泌恶性瘤.
手术后的铁血球蛋白 (Tg) 水平是监测治疗反应和复发的关键标志物.
在PTC中淋巴结比率 (LNR) 的预后值需要进一步阐明.

研究的目的:

在被诊断为乳头甲状腺癌 (PTC) 的患者中,研究淋巴结比率 (LNR) 和术后甲状腺蛋白 (Tg) 水平之间的关联.

主要方法:

一项回顾性队列研究,涉及300名PTC患者.
分析临床病理变量,包括LNR,以及它们与术后未受刺激的Tg (uTg),预消化刺激的Tg (sTg) 和后消化刺激的Tg水平的相关性.
使用多变量逻辑回归来确定Tg水平的独立预测因子.

主要成果:

在PTC患者中,LNR与术后的UTg,预消耗性stg和稳定后的UTg水平独立相关.
诸如M分类和术后甲状腺刺激激素水平等因素也与术后的Tg相关.
放射性 (RAI) 治疗剂量和M分类与前置和后置Tg水平相关.

结论:

淋巴结比率 (LNR) 是皮肤状甲状腺癌中手术后甲状腺蛋白水平的独立预测指标.
患有较高LNR的患者在手术治疗后更容易出现不完全的生化缓解.
在PTC的管理中,LNR作为一个有价值的预后指标.

关键词:

生物化学不完整的反应淋巴结比率是淋巴结的比率.转移转移转移转移乳头甲状腺癌是一种乳头甲状腺癌.放射性是一种放射性.甲状腺球蛋白是一种甲状腺蛋白.

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