饮食炎症指数与肥胖成年人全因死亡率之间的关联
Xin Zheng1,2,3, Yi-Zhong Ge1,2,3,4, Guo-Tian Ruan1,2,3
1Department of Gastrointestinal Surgery/Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
通过饮食炎症指数 (DII) 衡量的促炎症饮食,增加了腹部肥胖和超重/肥胖的成年人全因死亡风险. 这种关联在男性中比女性更强,炎症起着调解作用.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
- 以前的研究将促炎症饮食与肥胖和慢性疾病联系起来.
- 肥胖患者的DII和死亡率之间的关联仍在调查中.
研究的目的:
- 调查饮食炎症指数 (DII) 与全因死亡率之间的关联.
- 为了检查腹部肥胖和简单超重或肥胖的成年人之间的这种关联.
- 探索性别差异和系统性炎症的调解作用.
主要方法:
- 利用美国国家健康和营养检查调查 (NHANES) 数据 (2007-2018).
- 定义了一种促炎饮食,即DII > 0.
- 采用考克斯回归分析和受限立方线来评估DII-死亡率关联,包括调解分析.
主要成果:
- 促炎症饮食显著增加了腹部肥胖 (aHR: 1.31) 和简单超重/肥胖 (aHR: 1.30) 的成年人全因死亡率.
- 在最高的DII四分位数中,这些群体的死亡风险分别增加了43%和39%.
- 与男性相比,女性对促进炎症饮食的影响有更强的抵抗力;白细胞和中性粒细胞数量介导了DII-死亡率的联系.
结论:
- 促炎症饮食与肥胖成年人全因死亡率的增加有关.
- 促炎症饮食对死亡率的影响在性别之间有所不同.
- 通过白细胞和中性粒细胞计数表明的全身炎症可能会调解这种关联.
更多相关视频
09:10Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
Published on: November 1, 2019
03:35Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
Published on: December 1, 2023
相关概念视频
Obesity
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Coronary Artery Disease I: Introduction
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
