高标位 (>200 g/L) 乳酸生产从未排毒的预处理玉米炉
Yuwei Zhang1, Zhaoxian Xu1, Minrui Lu1
1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China; Biorefinery Research Institution, Nanjing University of Science and Technology, Nanjing 210094, China.
Bioresource technology
|September 10, 2023
概括
这项研究开发了一种生物炼油系统,用于从玉米中生产纤维素乳酸. 它实现了创纪录的高乳酸度,使得基纤维素生物质发酵的有效扩展成为可能.
科学领域:
- 生物技术是生物技术.
- 生物化学工程 生物化学工程
- 可持续化学 可持续化学
背景情况:
- 基纤维素生物质为乳酸生产提供可持续的原料.
- 在发酵过程中产品度低,阻碍了纤维素乳酸的大规模制造.
研究的目的:
- 开发和演示一个生物炼油系统,以高效地从纤维素生物质中生产纤维素乳酸.
- 为了优化发酵参数,包括细菌菌株,模式,固体载荷和容器类型.
主要方法:
- 石纤维素生物质 (玉米炉) 的化学预处理 (硫酸).
- 开发一种同时糖化和共发酵 (SSCF) 过程.
- 评估各种乳酸细菌菌株和发酵条件.
主要成果:
- 几种乳酸细菌在高固体加载的玉米炉水解剂中表现出高发酵活性.
- 通过使用SSCF在100毫升瓶中从40%固体加载玉米炉水解剂中获得210.1g/L的乳酸.
- 在3L生物反应器中使用SSCF从35%固体加载玉米炉水解液中获得157.4g/L乳酸.
结论:
- 开发的生物炼油系统显著提高了来自基纤维素生物质的乳酸标位.
- 取得的高标位代表了高效,大规模的纤维素乳酸生产的突破.
- 这种方法验证了玉米作为工业乳酸发酵的可行基质的潜力.
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