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在低收入和中等收入国家抑郁症的认知表现:一个系统性审查与元分析组件

Pauline Thibaut¹, Rukudzo Mwamuka², Primrose Nyamayaro²

¹Department of Health Service & Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Journal of affective disorders

|September 10, 2023

概括

抑郁症在低收入和中等收入国家 (LMIC) 显著影响认知,特别是记忆. 这些地区的研究突出了理解和解决与抑郁症相关的认知缺陷的关键差距.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
全球健康全球健康

背景情况:

抑郁症是低收入和中等收入国家 (LMIC) 普遍存在的心理健康问题.
认知功能障碍是抑郁症的常见症状,但在LMIC中对其评估的研究不足.
需要了解LMIC中抑郁症研究中使用的神经认知测试.

研究的目的:

在LMIC中调查抑郁症患者的认知表现.
系统地审查在LMIC进行的抑郁症研究中使用的神经认知测试.

主要方法:

在主要数据库 (APA PsycInfo,Embase,Ovid MEDLINE,全球健康) 进行了系统的文献搜索.
研究包括在LMIC内的抑郁人口中实施的认知性能测试.
使用跨文化适应量表来评估工具质量,并提取人口统计,抑郁和认知指标的数据.

主要成果:

分析了29项涉及11个LMIC国家的19100名参与者的研究,其中大多数研究是在中高收入国家进行的.
使用了67种广泛的认知性能工具,但可靠性 (5.6%) 和有效性 (8.3%) 报告较低,只有36.1%是文化适应的.
抑郁群体始终表现出认知缺陷,特别是记忆 (科恩d = -1.60),其中75.9%的研究包括记忆测试.

结论:

在LMIC中,认知障碍,特别是记忆障碍在抑郁症中很普遍.
这项研究强调了在LMIC中抑郁症中认知功能障碍的重大负担.
有一个显著的研究差距存在关于认知评估的抑郁症在LMIC,表明需要更强大的和文化相关的方法.

关键词:

认知障碍认知障碍是一种认知障碍.认知表现指标是认知表现的指标.低收入和中等收入国家.大型抑郁症主要是抑郁症.

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