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Updated: Jul 16, 2025

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae
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FLASH-RT不会影响染色体转位和结结构,超出CONV-RT剂量率的影响

Paul G Barghouth1, Stavros Melemenidis1, Pierre Montay-Gruel2

  • 1Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
|September 10, 2023
PubMed
概括

超高剂量速率放射治疗 (FLASH-RT) 与传统剂量速率放射治疗 (CONV-RT) 相比,没有减少染色体转位. 在FLASH-RT和CONV-RT之间,无论氧气水平如何,DNA双链断裂修复和转位形成是相似的.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.染色体转位是染色体的转位.这是一个FLASH-RT.在HTGTS-JoinT-seqq中使用.氧气过低是因为缺氧.

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