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喉镜外观与声囊囊中的组织病理学之间的相关性
Daniel A Alfonso-Ying1, Christine M Clark1, Theresa Scognamiglio2
1Sean Parker Institute for the Voice, Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medicine, New York, New York.
Journal of voice : official journal of the Voice Foundation
|September 10, 2023
概括
在喉腔镜检查中,声囊的出现并不能可靠地预测其病理学. 位置,而不是不透明度,与囊类型相关,影响这些良性声病变的诊断和治疗.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 喉腔病学是指喉科的医生.
- 病理学 病理学 病理学
背景情况:
- 声囊是一种常见的良性病变.
- 粘膜保留和表皮囊是典型的亚型.
- 目前的理解表明,半透明囊是粘液保留,不透明囊是表皮状.
研究的目的:
- 调查声囊的临床特征及其本病理学发现之间的关系.
- 挑战囊外观和组织病理学相关性的传统范式.
主要方法:
- 对临床人口统计数据,视频视野镜检查和基因病理学的回顾性审查.
- 该研究包括了2006年至2021年间经过手术切除声囊的成年患者.
主要成果:
- 分析了69名患者的数据.
- 囊的不透明度与组织病理学没有相关性 (P=0.415).
- 低膜和上表面囊显示出特定的上皮关联 (P=0.003,P=0.002).
- 表皮质囊更频繁地与临床炎症相关 (P=0.002).
结论:
- 临床外观,特别是不透明度,不是声囊组织病理学的可靠指标.
- 囊的位置是表皮类型的更重要的预测因素.
- 研究结果表明,需要重新评估声囊的诊断方法.
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