在第三级护理瘤中心的献血者和患者样本中的 ABO 血型差异:分析和血清学解决方案
Priti Desai1, Anisha Navkudkar1, Sunil Rajadhyaksha1
1Tata Memorial Centre, HBNI, Mumbai, Maharashtra, India.
Hematology, transfusion and cell therapy
|September 10, 2023
概括
ABO血型差异,特别是抗原减弱/缺失,在献血者和瘤患者中都是常见的. 彻底的血清检查对于准确的血型和安全的输血至关重要.
科学领域:
- 输血医学 输血医学
- 血清学 血清学是一门学科.
- 血液学 血液学 血液学
背景情况:
- 准确的 ABO 血型分组涉及抗原类型和抗体查.
- 细胞和血清分组之间的差异需要调查.
- 了解 ABO 差异对于输血安全至关重要.
研究的目的:
- 为了确定ABO血型差异的发生率和原因.
- 为了分析健康的献血者和瘤学患者之间的差异.
- 突出解决 ABO 差异的重要性.
主要方法:
- 在献血者和瘤患者样本中分析了ABO差异 (2015年1月至2018年12月).
- 使用列凝结试验进行的 ABO 血液分组.
- 详细的血清学检查,以解决发现的差异.
主要成果:
- 从76,604个供体和134,964个患者样本中发现了117个ABO差异.
- 弱化/缺少抗原是两组中最常见的原因 (38%的捐赠者,27%的患者).
- 其他原因包括抗体减弱/缺失,泛质化和各种因素.
结论:
- 弱化/缺失的抗原差异是捐赠者和患者群体中占主导地位的类型.
- 完整的血清检查对于准确的血型报告至关重要.
- 解决差异可以确保为患者提供适当的输血管理.
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