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Updated: Jul 16, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
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一个深度静止的CML LSC子集依赖于粮农组织,但通过抑制线粒体复合体I来避免有害的ROS

Nyam-Osor Chimge1, Min-Hsuan Chen2, Cu Nguyen1

  • 1Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

Current molecular pharmacology
|September 11, 2023
PubMed
概括

慢性骨髓性白血病 (CML) 中的深静止白血病干细胞 (LSC) 通过抑制线粒体复合物I (MC-1) 和依赖脂肪酸氧化 (FAO) 来避免ROS. 一种CBP/β-catenin对抗剂ICG-001诱导LSC的分化并使它们对伊马替尼治疗重新敏感.

关键词:
美国中央银行 (CBP) 的CBP.在CML中,CML是CML.在ICG-001.1.下面,我们来看看ICG-001.1.在这里,我们可以看到LiLiLiLiLi.在LSC的LSC上.在MC-1中,我们可以使用MC-1.代谢过程中的代谢.

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