在急诊室的未引起的急性静脉血栓栓塞症中增加红细胞分布宽度的预测值
Cláudia Febra1,2, Verónica Spinu3, Filipa Ferreira3
1Department of Intensive Care, Hospital da Luz Lisboa, Lisbon, Portugal.
概括
红细胞分布宽度 (RDW) 是急性未引起的静脉血栓塞栓症 (VTE) 的潜在早期指标. 14%或更高的RDW可能有助于识别需要进一步诊断VTE的患者.
科学领域:
- 血液学 血液学 血液学
- 紧急医疗 紧急医疗
- 诊断生物标志物 诊断生物标志物
背景情况:
- 急性静脉血栓栓塞 (VTE),包括肺栓塞和深静脉血栓塞 (DVT),是一种常见的急诊室表现.
- 由于非特定的临床症状和生物标志物,诊断未引起的VTE具有挑战性,往往导致治疗延迟.
- 早期识别VTE对于及时和适当的患者管理至关重要.
研究的目的:
- 调查红细胞分布宽度 (RDW) 作为急性未引起的VTE早期诊断标记物的潜力.
- 确定RDW在诊断急诊室患者的静脉动脉突发症中的准确性,敏感性和特异性.
主要方法:
- 一项前性观察性研究包括向ED提出疑似未引起的急性VTE的患者.
- 收集了临床和实验室数据,并在VTE阳性和VTE阴性组之间进行了比较.
- 使用接收器操作特征 (ROC) 分析来确定VTE诊断的最佳RDW切断点.
主要成果:
- 诊断为VTE的患者在ED入院时显示出较高的RDW水平 (14.3%),与非VTE患者 (13.5%) 相比.
- 一个RDW切断值≥14%证明了良好的区分值 (AUC = 0.685) 预测未引起的VTE.
- RDW ≥14%被确定为成年患者未引起的静脉瘤的独立预测因子,特别是在孤立的DVT病例中.
结论:
- 在急诊室入院时红细胞分布宽度 (RDW) 升高与急性未引起的深静脉血栓塞 (DVT) 有显著的关联.
- 14%或更高的RDW水平作为成人患者未引起的静脉瘤的独立预测指标.
- RDW可能有助于早期识别急性未引起的VTE患者,可能减少诊断延迟.
相关概念视频
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
14
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
14
Venous Thrombosis I: Introduction
12
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
12
Venous Thrombosis III: Interprofessional Care
10
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
10
Venous Thrombosis IV: Nursing Management
14
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
14
Assessment of the Cardiovascular System III: Palpation
376
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
376
Venous Return
5.1K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
5.1K


