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通过抑制T细胞中的Pdcd1表达,CBX4促进抗瘤免疫力

Liwei Ren1, Ziyin Li1, Yu Zhou2

  • 1Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Peking University, Beijing, China.

Molecular oncology
|September 11, 2023
PubMed
概括

缺少CBX4蛋白质会通过增加PD-1表达和阻碍细胞因子的产生,从而降低T细胞抗瘤免疫力. 这种编程细胞死亡蛋白1 (PD-1) 的表观遗传调节会影响T细胞功能和瘤生长.

关键词:
这就是CBX4 CBX4.H2AK119ub1 在线观看在PD-1中使用PD-1.在PRC1中,T细胞的反应反应.抗瘤免疫力 免疫力

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