晚期膝关节骨关节炎的绝经后妇女接受手术治疗的身体组成和骨矿物质密度
Jung Yoon Park1, Youn-Jee Chung1, Jae-Yen Song1
1Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Journal of menopausal medicine
|September 11, 2023
概括
经历膝关节骨关节炎 (OA) 的绝经后妇女接受手术,体重过重/肥胖和形肥胖 (SO) 的比例很高. 肥胖可能会提供一些骨保护,但SO.
科学领域:
- 整形外科 整形外科 整形外科
- 老年学是一门学科.
- 代谢健康 代谢健康
背景情况:
- 膝关节关节炎 (OA) 在绝经后妇女中很普遍.
- 像全膝关节整形术这样的手术干预是高级OA的常见治疗方法.
- 肥胖和肉是影响骨健康和OA进展的重要并发症.
研究的目的:
- 为了评估经绝经后妇女的骨矿物质密度 (BMD) 和身体组成,膝盖OA手术后.
- 调查形肥胖症 (SO) 的患病率及其与肥胖症标志物的关系.
- 为了探索肥胖和肉类病对骨健康的影响,在这个患者队列.
主要方法:
- 这项研究包括254名绝经后 (50岁以上) 患有膝盖骨关节炎的女性,她们接受了手术治疗.
- 使用双能X射线吸收计 (DXA) 评估与肥胖相关的因素,肌肉质量和BMD.
- 使用多个肥胖指标 (BMI,内脏脂肪组织,身体脂肪百分比) 定义了sarcopenic肥胖 (SO).
主要成果:
- 在膝关节OA患者的症状和逆侧腿之间,部BMD没有显著差异.
- 在肥胖组观察到更高的BMD (按BMI定义).
- 根据不同肥胖症定义,形肥胖 (SO) 的患病率在22.0%至49.6%之间.
结论:
- 经过手术的晚期膝关节OA患者表现出高超重/肥胖和SO的高率.
- 肥胖可能会对骨密度产生复杂的,潜在的保护作用,可能是由于承重.
- 需要进一步的研究来阐明SO对骨密度和OA结果的具体影响.
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