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Updated: Jul 16, 2025

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开拓性活动区分了激活和非激活的SOX2结合位点

Michela Maresca1, Teun van den Brand1, Hangpeng Li2

  • 1Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

The EMBO journal
|September 11, 2023
PubMed
概括

像SOX2这样的先驱转录因子迅速保持色素的开放. 只有SOX2维护的可访问部位,而不是所有结合部位,直接预测基因表达,揭示了关键的调节作用.

关键词:
急性蛋白质枯竭急性蛋白质枯竭染色质可访问性 染色质可访问性基因调节 基因调节 基因调节开拓者活动 开拓者活动转录因子是一种转录因子.

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