在心房患者的全血细胞计数中获得的炎症生物标志物
Özden Kutlay1, Zafer Yalım1, Arzu Keskin Aktan1
1Afyonkarahisar Health Sciences University.
Kardiologiia
|September 11, 2023
概括
血液学指数如中性粒细胞与淋巴细胞的比率 (NLR) 和单细胞与HDL的比率 (MHR) 可以帮助预测心房动 (AF). 作为早期AF检测的独立预测因子,MHR表现特别有前途.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 炎症标志物的炎症标志物
背景情况:
- 心房动 (AF) 是一种常见的心律失常.
- 炎症在心血管疾病中起作用.
- 完整血清 (CBC) 测试提供了可访问的生物标志物.
研究的目的:
- 调查AF与来自CBC测试的各种血液学指数之间的关系.
- 为了确定AF发展的潜在预测标记.
主要方法:
- 对150名AF患者和91名对照 (年龄在40-80岁) 的回顾性研究.
- 血液学指数的评价:NLR,MPV,PLR,MPV/PLT,NMR,LMR,SII,MHR. 这些指数均为血液学指数.
- 多变量回归和ROC曲线分析.
主要成果:
- 在AF患者中,NLR,PLR,SII,MHR,MPV/PLT的升高,以及LMR的降低.
- NLR,SII和MHR被确定为AF的独立预测因素.
- 在ROC分析中,MHR表现出100%的灵敏度和56%的特异性.
结论:
- 包括NLR,PLR,LMR,SII,MPV/PLT和MHR在内的血液学指数可能有助于早期AF预测.
- MHR成为AF发展的潜在强有力的独立预测因素.
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