案例报告:Kingella kingae导致成年人的假肢关节感染
Katherine Wensley1, Damian McClelland1, Natalie Grocott1
1Department of Trauma and Orthopaedics, Royal Stoke University Hospital, Stoke-on-Trent ST4 6QG, UK.
Access microbiology
|September 11, 2023
概括
大人的罕见病原体Kingella kingae可以感染假肢关节. 这一案例突显了假肢肩部感染的成功治疗,通过两阶段的修复和抗生素.
科学领域:
- 传染性疾病 传染性疾病
- 整形外科手术 整形外科手术
- 微生物学 微生物学
背景情况:
- 金氏菌 (Kingella kingae) 是一种格拉姆阴性细菌,很少涉及成年人感染.
- 虽然已知影响假体心脏门,但K. kingae以前没有报告感染成人假体关节.
研究的目的:
- 报告第一个成年人Kingella kingae假肢关节感染病例.
- 描述这种罕见感染的成功管理.
- 提高临床医生对K. kingae作为假肢关节感染中的潜在病原体的认识.
主要方法:
- 一个61岁的女性,有类风湿性关节炎病史,肩膀完全置换,呈现出排放性鼻.
- 患者接受了两阶段的修复肩部置换,包括脱bridement和植入物切除.
- 深层组织样本进行培养,患者接受了静脉注射塞夫,然后口服西普洛素的治疗.
主要成果:
- 从深层组织样本中,Kingella kingae被确定为致病原体.
- 患者成功完成了抗生素治疗,并接受了第二阶段的定制肩部置换.
- 在初始修复手术10个月后,可以实现良好的功能恢复.
结论:
- 临床医生应考虑Kingella kingae作为假肢关节感染的潜在原因,特别是在免疫抑制患者中.
- 双阶段修复关节整形术是一种有效的治疗策略,可以消除K. kingae假肢关节感染.
- 贝塔乳酸抗生素是推的治疗选择.
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