D-DI/PLT可以作为败血症的预后指标
Xiaojun Zhao1, Xiuhua Wu2, Yi Si1
1Department of Emergency, Xijing Hospital, Fourth Military Medical University, Xian, Shaanxi, China.
PeerJ
|September 11, 2023
概括
血小板对D-二分体的比率 (D-DI/PLT) 是败血症患者结果的强有力的预测指标. 高D-DI/PLT水平表明预后不佳,有助于早期评估败血症患者的风险.
科学领域:
- 关键护理医学 关键护理医学
- 血液学 血液学 血液学
- 生物化学 生物化学
背景情况:
- 败血症是一种危及生命的器官功能障碍,是由宿主对感染的反应失调引起的.
- 预后指标的早期识别对于改善败血症患者的治疗结果至关重要.
- 现有的生物标志物和评分系统在预测败血症预后方面存在局限性.
研究的目的:
- 确定影响早期败血症患者结果的关键指标.
- 评估已识别的指标在败血症的预后效果.
主要方法:
- 分析了201名败血症患者的临床数据.
- 根据28天生存率或死亡率对患者进行分组.
- 使用风险因素分析和ROC曲线确定了独立的风险因素.
主要成果:
- D-二分体 (D-DI),SOFA得分,血小板 (PLT),INR和D-DI/PLT比率是重要的指标.
- D-DI/PLT比率显示出高的预后效率 (AUC=93.9).
- 高的D-DI/PLT,D-DI,SOFA和低的PLT与28天生存率的降低有关.
结论:
- D-DI/PLT比率是导致败血症预后不佳的重要独立风险因素.
- D-DI/PLT 作为一种有价值的临床预测剂,可以预测败血症患者的结果.
- 这个比率可以帮助早期分层风险和治疗败血症.
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