在接受胃肠道手术的老年患者中,碳酸和乳酸的灵格溶液与乳酸的灵格溶液的疗效:一项前性随机对照试验
Jia Liu1, Yang Gao1, Ziqing He1
1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University Hefei 230022, Anhui, China.
American journal of translational research
|September 11, 2023
概括
与乳酸林格溶液 (LRS) 相比,二碳酸林格溶液 (BRS) 在接受胃肠道手术的老年患者中显著降低了术后的超乳糖血症和轻微并发症. BRS可能是这个患者群体的优越液体选择.
科学领域:
- 麻醉学和外科手术期间的医学.
- 胃肠道手术 胃肠道手术
- 关键护理医学 关键护理医学
背景情况:
- 在接受胃肠道手术的老年患者中,术后的乳糖过高是令人担忧的.
- 流体治疗的选择会影响代谢和临床结果.
- 乳酸林格溶液 (LRS) 是常用的,但它对乳酸代谢的影响需要研究.
研究的目的:
- 在接受胃肠道手术的老年患者中,比较二碳酸林格溶液 (BRS) 与LRS的疗效.
- 评估BRS对乳酸代谢,酸平衡和临床结果的影响.
- 为了确定影响术后乳酸度的因素.
主要方法:
- 对60名接受胃肠道手术的老年患者进行前性随机受控研究.
- 患者接受了以BRS (n=30) 或LRS (n=30) 的目标导向液体治疗.
- 主要结局:术后高乳糖血的发生率;次要结局:酸平衡,肝功能和30天内的并发症.
主要成果:
- 在BRS组中,高乳糖血症的发病率较低 (3.3%对40.0%,P<0.001).
- BRS组显示轻微并发症风险降低 (50.0%对76.7%,P=0.032),尤其是肝功能受损 (16.7%对43.3%,P=0.024).
- 两组之间没有pH值,二碳酸盐,过多,重大并发症或住院时间的显著差异.
结论:
- 二碳酸盐林格溶液 (BRS) 在减轻术后的乳糖过高和小并发症方面更有效,在接受胃肠道手术的老年患者中.
- 对于这个特定的患者群体,BRS可能代表一个更有益的外科手术周流体治疗选择.
- 糖尿病,低血压和LRS输注量是与乳酸度相关的关键因素.
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