在老年人中,达到促使活力减少的努力成本
bioRxiv : the preprint server for biology
|September 11, 2023
概括
由于能源成本增加,老化减缓了运动速度,而不是降低了奖励估值. 老年人花费更多的能量以相同的速度移动,使得较慢的运动成为适应性的经济选择.
科学领域:
- 神经科学是一个神经科学.
- 运动科学 运动科学
- 老年学是指老年学的学科.
背景情况:
- 健康的衰老与运动活力 (速度) 的减少有关.
- 这种减速可能是由于奖励灵敏度下降或能量消耗增加.
- 了解底层机制对于干预至关重要.
研究的目的:
- 调查与年龄相关的运动减缓主要是由奖励估值变化或代谢努力成本增加所驱动的.
- 使用可量化的指标,区分基于奖励和基于努力的运动活力的变化.
主要方法:
- 量化了年轻人和老年人在达到运动时消耗的代谢能量.
- 评估了奖励大小如何调节两个年龄组的运动启动和速度.
- 研究了增加努力对年轻成年人运动奖励调节的影响.
- 开发了一个计算模型来分析运动活力变化.
主要成果:
- 老年人花费的代谢能量比年轻人要多得多,以达到给定的速度.
- 虽然老年人更早地开始运动,以回应更高的奖励,但他们的运动速度与年轻人相比显示出较少的调制.
- 年轻人增加的努力模仿了衰老的影响,主要是增加反应时间,对运动速度的影响最小.
结论:
- 运动的代谢成本增加,而不是奖励估值降低,显著导致与年龄相关的减速.
- 衰老中的较慢运动似乎是对更高的能量需求的合理适应.
- 对代谢成本和奖励敏感性的客观测量可以区分与衰老相关的运动变化.
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