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Updated: Jul 29, 2026

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
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Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

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在α-synuclein中的A53T突变增强了人类微质中的促炎激活

Marine Krzisch, Bingbing Yuan, Wenyu Chen

    bioRxiv : the preprint server for biology
    |September 11, 2023
    PubMed
    概括

    帕金森病 (PD) 中突变的α-synuclein导致人类微质细胞变得更加炎症,并经历了增加的氧化应激. 这种细胞自主功能障碍可能会在早期发病的PD中恶化神经退行.

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