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Updated: Jul 16, 2025

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精密蛋白形设计用于4R Tau 异形选择性模板聚合的精密蛋白形设计.

Andrew P Longhini1,2, Austin DuBose3, Samuel Lobo4

  • 1Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California, USA.

bioRxiv : the preprint server for biology
|September 11, 2023
PubMed
概括

陶纤维通过选择性播种4R陶聚合物来传播陶病. 异形中的特定氨基酸变化显著改变了这种播种过程,这表明针对异病的向治疗策略.

关键词:
氨基化原核的核心生物科学 生物科学神经科学是一个神经科学.像Prion这样的模板设计蛋白质的错误折叠 蛋白质的错误折叠陶氏病变 (tauopathies) 是一种疾病.

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