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Updated: Jul 16, 2025

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation
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一个工程核酶编辑器,用于增强向基因组集成

Hangu Nam, Keqiang Xie, Ishita Majumdar

    bioRxiv : the preprint server for biology
    |September 11, 2023
    PubMed
    概括

    我们开发了enGager,这是一种新的系统,通过改善DNA模板到目标站点的传递来增强基因编辑. 这种系统显著提高了大型转基因整合的效率,特别是在初级细胞中,为先进的基因疗法铺平了道路.

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