对比度灵敏度:在V1损伤后恢复视力的基本限制
Jingyi Yang1,2,3, Elizabeth L Saionz1,3, Matthew R Cavanaugh1,3
1Flaum Eye Institute, University of Rochester Medical Center, Rochester, New York 14642.
medRxiv : the preprint server for health sciences
|September 11, 2023
概括
在初级视觉皮层 (V1) 中风后的视觉重新训练在盲人领域恢复对比度敏感性 (CS) 方面取得了有限的成功. 虽然看到了一些改善,但没有达到正常的CS,这表明CS的不同神经基质.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 康复医学 康复医学 康复医学
背景情况:
- 初级视觉皮层 (V1) 中风导致显著的视觉缺陷.
- 感知再训练可以改善中风后的一些视觉功能.
- 与方向/方向歧视相比,对比度敏感度 (CS) 的恢复是有限的.
研究的目的:
- 调查V1中风盲场中对比度敏感性 (CS) 的保存.
- 确定CS保存的程度和视觉训练的潜在益处.
- 在亚急性和慢性V1中风患者中比较CS恢复.
主要方法:
- 招募了亚急性 (<3个月) 和慢性 (>6个月) V1中风患者.
- 评估了基线方向和方向歧视CS在盲目场.
- 使用Gabor补丁在不同对比度,闪或运动下进行视觉训练.
主要成果:
- 更多的亚急性患者最初在盲场中歧视高对比度方向.
- 所有参与者都无法区分低对比度的刺激,即使添加了闪或运动.
- 与慢性患者相比,训练在更多的亚急性患者中改善了CS,但没有一个达到正常水平.
结论:
- 在V1损伤后恢复对比度敏感性 (CS) 在成年时具有有限的能力.
- 在V1中风后,CS恢复不如导向/方向歧视那么成功.
- CS可能涉及不同的神经基质和计算,而不是V1.1中的定向/方向歧视.
相关概念视频
Photoreceptors and Visual Pathways
6.1K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.1K
Color Vision
611
Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
611
Vision
53.5K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
53.5K
Anatomy of the Eyeball
7.2K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.2K
Visual Agnosia
234
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
234
Visual System
613
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
613


